Flung through a cosmic wormhole, American astronaut John Crichton finds himself fighting for his life in the middle of an alien prison break, inside a Leviathan — a living space ship — on the far side of the galaxy. Hunted by the relentless Crais, a commander of the galactic enforcers known as Peacekeepers, Crichton joins forces with the alien convicts — hulking warrior Ka D'Argo; blue-skinned Priestess Zhaan; diminutive Dominar Rigel XVI; the giant symbiote Pilot and the “irreversibly contaminated” Peacekeeper Aeryn Sun. Each desperately seeks a way home, but first, they have to find a way to trust one another. Daring escapes and selfless acts of courage forge a measure of loyalty, friendship and even love.
